Angelica Zachary got married to Marlon Wayans in 2005 and got divorced from him 8 years later. This marriage produced two children, a boy and a girl- Shawn Howell Wayans and Amai Zackery Wayans.

Apart from her relationship with her ex-husband, there are no details about her being in a relationship with another man. Although she might not be single at the moment, not much is known about her current relationship.

While Angelica Zachary and Marlon Wayans did not date for a long time before getting married, they already knew each other much earlier. They got to know each other in the 1990s.

Her husband, Wayans, who is also an actor, has appeared in other films including Norbit (2007), G.I. Joe: The Rise of Cobra (2009), The Heat (2013), A Haunted House (2013) and its sequel A Haunted House 2 (2014), Naked (2017), Fifty Shades of Black (2016), Sextuplets (2019), and On the Rocks (2020).

He partnered with Randy Adams to create What the Funny, an online destination for urban comedy. Wayans created the comedy competition television show Funniest Wins, which aired on TBS in 2014.

Since 2014, Wayans and his brothers have been traveling the U.S. with “The Wayans Brothers Tour”. In 2017, he began starring in his own NBC sitcom Marlon, which ran for two seasons.